Trifluridine — supply status, manufacturers & alternatives

Trifluridine

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🇦🇺 AUST R 273238 · Servier Laboratories Australia Pty Ltd

In supply · Australia

Virophta, préparation pour collyre –

In supply · 🇦🇺 Australia · short in🇫🇷 FR

In supply in Australia

Reading today’s signals…

🇦🇺 AUAEMPA$707.14DPMQ A$2322.00details →

✓ Can I substitute?

In supply

no shortage substitution needed

⇄ Best alternative

None listed

refer to prescriber

◷ Expected back

No estimate

No estimate provided

Product attributes reference data we hold

Active ingredient (INN)	Trifluridine

Brand names	Virophta, préparation pour collyre –

Therapeutic category	Auto-created by Agence nationale de sécurité du médicament — Disponibilité scraper

Controlled substance	No

Marketing-authorisation holders	Servier Laboratories Australia Pty Ltd, SANDOZ INC, APOTEX INC, SANDOZ CANADA INCORPORATED

Registrations on file	7

Patient information leaflet (PIL)	Not on file

Summary of product characteristics (SPC)	Not on file

Trade price 🇦🇺 PBS · July 2026

🇦🇺 AU

● Official price on file

Ex-manufacturer

A$707.14

AEMP

Dispensed (DPMQ)

A$2322.00

incl. fees

Pack

trifluridine 15 mg + tipiracil 6.14 mg tablet, 20

Source: PBSEffective July 2026 · AUD

Other markets

🇺🇸 US

US$23.94

Acquisition

Substitution pathways 🇦🇺 Australia · TGA

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No substitution instrument in force

Dispense per normal rules, or refer to the prescriber. No active SSSI/S19A instrument detected for this medicine.

Global API supply base 🇺🇸 FDA Drug Master Files · active Type II

7 API manufacturers

Manufacturers with an active Type II Drug Master File — i.e. cleared to supply this active ingredient into the US market. A proxy for how concentrated the global manufacturing base is.

Low concentration risk

Natco Pharma LTDYuki Gosei Kogyo CO LTDBiophore India Pharmaceuticals PVT LTDMsn Laboratories Private LTDIntas Pharmaceuticals LTDApitoria Pharma Private LTD+1 more

Manufacturing countries: India, Japan · Source: FDA List of Drug Master Files

Registration recordmarketing-authorisation holders

Registrations & marketing-authorisation holders7 registrations · 4 MA holders

Product	Strength	Form	Market	MA holder	Status
Lonsurf	20 mg	—	🇦🇺 AU	Servier Laboratories Australia Pty Ltd	Active
Orcantas	15 mg	—	🇦🇺 AU	Servier Laboratories Australia Pty Ltd	Active
Orcantas	20 mg	—	🇦🇺 AU	Servier Laboratories Australia Pty Ltd	Active
Lonsurf	15 mg	—	🇦🇺 AU	Servier Laboratories Australia Pty Ltd	Active
Trifluridine	10mg/mL	solution	🇺🇸 US	SANDOZ INC	Active
Apo-Trifluridine Ophthalmic	—	solution	🇨🇦 CA	APOTEX INC	Active
Sandoz Trifluridine	—	solution	🇨🇦 CA	SANDOZ CANADA INCORPORATED	Active

For health-professional reference only. Mederti aggregates shortage and substitution information from official regulatory sources. It is not clinical advice and data may be incomplete or delayed. Confirm any substitution or supply decision against the primary regulator source, the prescriber, and current clinical references (e.g. AMH) before acting. Terms.