Propofol shortage — IT supply status & alternatives

Propofol

—

🇦🇺 AUST R 220082 · B Braun Australia Pty Ltd

In shortage · Australia

WHO Essential Medicine

PROVIVE 1% propofol

In declared shortage · 🇦🇺 Australia & also short in🇮🇹 IT🇨🇦 CA🇩🇪 DE🇺🇸 US🇧🇪 BE🌐 CO🇬🇷 GR🌐 MY+1

Critical shortage

Product discontinued / no longer available on the Australian market.

Reading today’s signals…

• Can I substitute?

No pathway on record

prescriber decision required

Product attributes reference data we hold

Active ingredient (INN)	Propofol
Brand names	PROVIVE 1% propofol
Therapeutic category	Auto-created by Therapeutic Goods Administration — Medicine Shortages scraper
WHO Essential Medicine	Yes · 1.1.2. General anaesthetics and oxygen > Injectable medicines (2023)
Controlled substance	No
Marketing-authorisation holders	BAXTER HEALTHCARE LIMITED, B Braun Australia Pty Ltd, B BRAUN MELSUNGEN AG, SANDOZ LIMITED +7 more
Registrations on file	24
Patient information leaflet (PIL)	Not on file
Summary of product characteristics (SPC)	Not on file

Trade price 🇦🇺 Australia · awaiting price ingest

🇦🇺 AU

Ex-manufacturer

—

Dispensed (DPMQ)

—

Pack

—

Not yet captured for Australia

Official pricing isn’t on file for this market yet. PBS (Australia), NHS Drug Tariff (United Kingdom) and CMS NADAC (United States) feeds are prioritised; this panel populates automatically once the data lands.

Other markets

🇺🇸 US

US$0.17

Acquisition

Global API supply base 🇺🇸 FDA Drug Master Files · active Type II

7 API manufacturers

Manufacturers with an active Type II Drug Master File — i.e. cleared to supply this active ingredient into the US market. A proxy for how concentrated the global manufacturing base is.

Low concentration risk

Curia Italy SrlBachem SASi GroupEmcure Pharmaceuticals LTDNeuland Laboratories LTDMidas Pharma GMBH+1 more

Manufacturing countries: Italy, Switzerland, United States, India, China · Source: FDA List of Drug Master Files

Shortage status by regulator official notices

🇦🇺

Australia

TGA · 3h ago

Critical

🇮🇹

Italy

AIFA · 1d ago

Critical

🇨🇦

Canada

HC · 3h ago

High

🇩🇪

Germany

BfArM · 3d ago

High

🇺🇸

United States

ANSM Ruptures · 3mo ago

High

🌐

INVIMA · 3h ago

Medium

🌐

NPRA · 2d ago

Medium

🇬🇷

EOF · 2d ago

Medium

Recalls official enforcement reports

🇺🇸

PROPOFOL

Pfizer Inc. · Aug 2022

Class Idetails ↗

🇺🇸

PROPOFOL

Pfizer Inc. · July 2022

Class Idetails ↗

🇺🇸

DIPRIVAN

Mckesson Medical-Surgical Inc. Corporate Office · Apr 2022

Class IIdetails ↗

🇺🇸

DIPRIVAN

Mckesson Medical-Surgical Inc. Corporate Office · Apr 2022

Class IIdetails ↗

🇺🇸

PROPOFOL

Hospira Inc. · Dec 2014

Class IIdetails ↗

🇺🇸

PROPOFOL

Hospira Inc. · Oct 2014

Class Idetails ↗

Sources official regulators

🌐

INVIMA

verified 3h ago

verify ↗

🇨🇦

verified 3h ago

verify ↗

🇦🇺

TGA

verified 3h ago

verify ↗

🇮🇹

AIFA

verified 1d ago

verify ↗

🌐

NPRA

verified 2d ago

verify ↗

🇬🇷

EOF

verified 2d ago

verify ↗

🇧🇪

FAMHP

verified 2d ago

verify ↗

🇳🇱

CBG-MEB

verified 2d ago

verify ↗

Registration recordmarketing-authorisation holders

Registrations & marketing-authorisation holders24 registrations · 11 MA holders

Product	Strength	Form	Market	MA holder	Status
PROPOFOL 10 MG/ML EMULSION FOR INJECTION/INFUSION	10 MG	injection	🇬🇧 GB	BAXTER HEALTHCARE LIMITED	Active
PROPOFOL 20 MG/ML EMULSION FOR INJECTION/INFUSION	20 MG	injection	🇬🇧 GB	BAXTER HEALTHCARE LIMITED	Active
Lipuro 1%	1%	—	🇦🇺 AU	B Braun Australia Pty Ltd	Active
Lipuro 2%	2%	—	🇦🇺 AU	B Braun Australia Pty Ltd	Active
Propofol 1% Emulsion For Injection Or Infusion	1%	injection	🇬🇧 GB	B BRAUN MELSUNGEN AG	Active
Propofol 2% Emulsion For Injection Or Infusion	2%	injection	🇬🇧 GB	B BRAUN MELSUNGEN AG	Active
PROPOFOL 10 MG/ML (1%) EMULSION FOR INJECTION/INFUSION	10 MG	injection	🇬🇧 GB	SANDOZ LIMITED	Active
PROPOFOL 20 MG/ML (2%) EMULSION FOR INJECTION/INFUSION	20 MG	injection	🇬🇧 GB	SANDOZ LIMITED	Active
Propofol 1% Emulsion For Injection/Infusion	1%	injection	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
Propofol 2% Emulsion For Injection/Infusion	2%	injection	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
Propofol 1% Emulsion For Injection/Infusion In Pre-Filled Syringe	1%	injection	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
Propofol 2% Emulsion For Injection/Infusion In Pre-Filled Syringe	2%	injection	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
PROPOFUSOR 1% propofol	1%	—	🇦🇺 AU	—	Active
PROPOFOL 10MG/ML (1%) EMULSION FOR INJECTION OR INFUSION	10MG	injection	🇬🇧 GB	ASPEN PHARMA TRADING LIMITED	Active
PROPOFOL 20MG/ML (2%) EMULSION FOR INJECTION OR INFUSION	20MG	injection	🇬🇧 GB	ASPEN PHARMA TRADING LIMITED	Active

+9 more registrations on file

For health-professional reference only. Mederti aggregates shortage and substitution information from official regulatory sources. It is not clinical advice and data may be incomplete or delayed. Confirm any substitution or supply decision against the primary regulator source, the prescriber, and current clinical references (e.g. AMH) before acting. Terms.